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Literature summary for 2.7.7.3 extracted from
- Biosynthesis of coenzyme A from phosphopantetheine from pantothenate (1954), J. Biol. Chem., 207, 767-773.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| cysteine | - |
Rattus norvegicus |  |
| cysteine | activation, in vitro | Sus scrofa | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Rattus norvegicus | 5829 | - |
| cytosol | - |
Sus scrofa | 5829 | - |
| cytosol | - |
Columba sp. | 5829 | - |
| mitochondrion | - |
Rattus norvegicus | 5739 | - |
| mitochondrion | - |
Sus scrofa | 5739 | - |
| mitochondrion | - |
Columba sp. | 5739 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | - |
Rattus norvegicus | |
| Mg2+ | requirement, 2 mM | Sus scrofa | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + pantetheine 4'-phosphate | Rattus norvegicus | - |
diphosphate + 3'-dephospho-CoA | - |
r | |
| ATP + pantetheine 4'-phosphate | Sus scrofa | - |
diphosphate + 3'-dephospho-CoA | - |
r | |
| ATP + pantetheine 4'-phosphate | Columba sp. | - |
diphosphate + 3'-dephospho-CoA | - |
r | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Columba sp. | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
| Sus scrofa | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial | Sus scrofa |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
| liver | - |
Sus scrofa | - |
| liver | - |
Columba sp. | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + pantetheine 4'-phosphate | - |
Rattus norvegicus | diphosphate + 3'-dephospho-CoA | - |
r | |
| ATP + pantetheine 4'-phosphate | - |
Sus scrofa | diphosphate + 3'-dephospho-CoA | - |
r | |
| ATP + pantetheine 4'-phosphate | - |
Columba sp. | diphosphate + 3'-dephospho-CoA | - |
r | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Rattus norvegicus |
| 37 | - |
assay at | Sus scrofa |
| 37 | - |
assay at | Columba sp. |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | - |
- |
Sus scrofa |
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