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Literature summary for 2.7.7.23 extracted from

  • Mok, M.T.; Tay, E.; Sekyere, E.; Glenn, W.K.; Bagnara, A.S.; Edwards, M.R.
    Giardia intestinalis: molecular characterization of UDP-N-acetylglucosamine pyrophosphorylase (2005), Gene, 357, 73-82.
    View publication on PubMed
Search for more literature for 2.7.7.23

Cloned(Commentary)

Cloned (Comment) Organism
expressed as His-tag fusion protein in Escherichia coli M15 Giardia intestinalis

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
48290
-
 calculated from the deduced amino acid sequence Giardia intestinalis
49624
-
 x * 49624, calculated from the deduced amino acid sequence of the His-tagged protein Giardia intestinalis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UTP + N-acetyl-alpha-D-glucosamine 1-phosphate Giardia intestinalis involved in the synthesis of UDP-N-acetyl-galactoseamine, which is required for cyst wall synthesis diphosphate + UDP-N-acetyl-D-glucosamine
-
 ?

Organism

Organism UniProt Comment Textmining
Giardia intestinalis Q8MUP8 Portland 1 strain, ATCC30888
-

Purification (Commentary)

Purification (Comment) Organism
recombinant protein using His-tag Giardia intestinalis

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
39.3
-
 purified recombinant enzyme Giardia intestinalis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UTP + N-acetyl-alpha-D-glucosamine 1-phosphate
-
 Giardia intestinalis diphosphate + UDP-N-acetyl-D-glucosamine
-
 ?
UTP + N-acetyl-alpha-D-glucosamine 1-phosphate involved in the synthesis of UDP-N-acetyl-galactoseamine, which is required for cyst wall synthesis Giardia intestinalis diphosphate + UDP-N-acetyl-D-glucosamine
-
 ?

Subunits

Subunits Comment Organism
? x * 49624, calculated from the deduced amino acid sequence of the His-tagged protein Giardia intestinalis