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Literature summary for 2.7.7.19 extracted from

  • Kashiwabara, S.I.; Tsuruta, S.; Yamaoka, Y.; Oyama, K.; Iwazaki, C.; Baba, T.
    PAPOLB/TPAP regulates spermiogenesis independently of chromatoid body-associated factors (2018), J. Reprod. Dev., 64, 25-31 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.7.19

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Mus musculus 5737
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + RNAn Mus musculus
-
 diphosphate + RNAn+1
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus Q9WVP6
-
-

Source Tissue

Source Tissue Comment Organism Textmining
spermatid
-
 Mus musculus
-
testis
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + oligo(A)18
-
 Mus musculus diphosphate + oligo(A)19
-
 ?
ATP + RNAn
-
 Mus musculus diphosphate + RNAn+1
-
 ?

Subunits

Subunits Comment Organism
? x * 70000, SDS-PAGE Mus musculus

Synonyms

Synonyms Comment Organism
PAPOLB/TPAP
-
 Mus musculus
poly(A) polymerase
-
 Mus musculus
poly[A] polymerase beta
-
 Mus musculus

General Information

General Information Comment Organism
malfunction enzyme-deficient mice exhibit spermiogenesis arrest and male infertility. Enzyme loss has no impact either on the abundance of chromatoid body components such as PIWIL1, TDRD6, YBX2, and piRNAs, or on retrotransposon expression Mus musculus
physiological function the enzyme regulates spermiogenesis through a pathway distinct from that mediated by chromatoid body-associated factors Mus musculus