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Literature summary for 2.7.7.19 extracted from

  • Furuya, N.; Kakuta, S.; Sumiyoshi, K.; Ando, M.; Nonaka, R.; Suzuki, A.; Kazuno, S.; Saiki, S.; Hattori, N.
    NDP52 interacts with mitochondrial RNA poly(A) polymerase to promote mitophagy (2018), EMBO Rep., 19, e46363 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.7.19

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Homo sapiens 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + RNAn Homo sapiens
-
 diphosphate + RNAn+1
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9NVV4
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HeLa cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + RNAn
-
 Homo sapiens diphosphate + RNAn+1
-
 ?

Subunits

Subunits Comment Organism
? x * about 60000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
MTPAP
-
 Homo sapiens
PapD1
-
 Homo sapiens
RNA poly(A) polymerase
-
 Homo sapiens
TUTase1
-
 Homo sapiens

General Information

General Information Comment Organism
malfunction enzyme knockdown reduces mitophagosome formation Homo sapiens
physiological function autophagy receptor NDP52 and the enzyme form an autophagy receptor complex, which enhances autophagic elimination of damaged mitochondria Homo sapiens