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Literature summary for 2.7.7.19 extracted from

  • Holbein, S.; Freimoser, F.M.; Werner, T.P.; Wengi, A.; Dichtl, B.
    Cordycepin-hypersensitive growth links elevated polyphosphate levels to inhibition of poly(A) polymerase in Saccharomyces cerevisiae (2008), Nucleic Acids Res., 36, 353-363.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
Polyphosphate with 20 nM to 0.002 mM of polyphosphate the length of the products is reduced but inhibition is not complete Bos taurus
Polyphosphate potent inhibitor of poly(A) polymerase activity, almost complete inhibition at 200 nM Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-
Saccharomyces cerevisiae
-
-
-
Saccharomyces cerevisiae BY4741
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + RNA
-
Saccharomyces cerevisiae diphosphate + RNA(A)n
-
?
ATP + RNA
-
Bos taurus diphosphate + RNA(A)n
-
?
ATP + RNA
-
Saccharomyces cerevisiae BY4741 diphosphate + RNA(A)n
-
?

Synonyms

Synonyms Comment Organism
PAP
-
Bos taurus
Pap1p
-
Saccharomyces cerevisiae
poly(A) polymerase
-
Saccharomyces cerevisiae
poly(A) polymerase
-
Bos taurus