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Literature summary for 2.7.7.18 extracted from

  • Orsomando, G.; Agostinelli, S.; Bramucci, M.; Cappellacci, L.; Damiano, S.; Lupidi, G.; Maggi, F.; Ngahang Kamte, S.; Biapa Nya, P.; Papa, F.; Petrelli, D.; Quassinti, L.; Sorci, L.; Vitali, L.; Petrelli, R.
    Mexican sunflower (Tithonia diversifolia, Asteraceae) volatile oil as a selective inhibitor of Staphylococcus aureus nicotinate mononucleotide adenylyltransferase (NadD) (2016), Ind. Crops Prod., 85, 181-189.
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Inhibitors

Inhibitors Comment Organism Structure
additional information Tithonia diversifolia (Mexican sunflower, flowerheads harvested in Dschang, West Province of Cameroon, Campus of Dschang University) essential oil is mostly active against Staphylococcusaureus and inhibits in vitro the pure NAD biosyntheticenzyme NadD from Staphylococcus aureus with IC50of of about 0.06 mg/ml, with basically none or only minor effects on mammalian orthologue enzymes, GC and NMR spectroemtric analysis of the essential oil composition, detailed overview. The essential oil of Maxican sunflower shows antibacterialand antioxidant activity, and cytotoxicity on human tumor cells Staphylococcus aureus

Organism

Organism UniProt Comment Textmining
Staphylococcus aureus P65502 gene nadD
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Staphylococcus aureus N315 P65502 gene nadD
-

Synonyms

Synonyms Comment Organism
nadD
-
 Staphylococcus aureus