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Literature summary for 2.7.7.18 extracted from
- Pathway of diphosphopyridine nucleotide biosynthesis in Escherichia coli (1961), J. Biol. Chem., 236, 1494-1497.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.03 | - |
nicotinate ribonucleotide | 37°C, pH 7.5 | Escherichia coli |  |
| 0.5 | - |
ATP | 37°C, pH 7.5 | Escherichia coli | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | requirement | Escherichia coli | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + nicotinate ribonucleotide | Escherichia coli | - |
diphosphate + deamido-NAD+ | - |
r | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
strains K-12 or B <3> | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial | Escherichia coli |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + nicotinate ribonucleotide | - |
Escherichia coli | diphosphate + deamido-NAD+ | - |
r | |
| ATP + nicotinate ribonucleotide | i.e. nicotinate mononucleotide | Escherichia coli | diphosphate + deamido-NAD+ | i.e. nicotinic acid adenine dinucleotide | r | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Escherichia coli |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | - |
- |
Escherichia coli |
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Release 2023.1 (January 2023)
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