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Literature summary for 2.7.7.18 extracted from

  • Imsande, J.
    Pathway of diphosphopyridine nucleotide biosynthesis in Escherichia coli (1961), J. Biol. Chem., 236, 1494-1497.
    View publication on PubMed

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.03
-
nicotinate ribonucleotide 37┬░C, pH 7.5 Escherichia coli
0.5
-
ATP 37┬░C, pH 7.5 Escherichia coli

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ requirement Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + nicotinate ribonucleotide Escherichia coli
-
diphosphate + deamido-NAD+
-
r

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
strains K-12 or B <3>
-

Purification (Commentary)

Purification (Comment) Organism
partial Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + nicotinate ribonucleotide
-
Escherichia coli diphosphate + deamido-NAD+
-
r
ATP + nicotinate ribonucleotide i.e. nicotinate mononucleotide Escherichia coli diphosphate + deamido-NAD+ i.e. nicotinic acid adenine dinucleotide r

Temperature Optimum [┬░C]

Temperature Optimum [┬░C] Temperature Optimum Maximum [┬░C] Comment Organism
37
-
assay at Escherichia coli

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
-
Escherichia coli