Literature summary for 2.7.7.15 extracted from

Awasthi, S.; Vivekananda, J.; Awasthi, V.; Smith, D.; King, R.J.
CTP:phosphocholine cytidylyltransferase inhibition by ceramide via PKC-a, p38 MAPK, cPLA2, and 5-lipoxygenase (2001), Am. J. Physiol., 281, L108-L118.

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Inhibitors

Inhibitors	Comment	Organism	Structure
C2 ceramide	-	Homo sapiens
lysophosphatidylcholine	generated as a consequence of the activation of cytosolic phospholipase A2 by protein kinase C-alpha and p38 mitogen-activated protein kinase	Homo sapiens
Tumor necrosis factor alpha	-	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
NCI-H441 cell	adult human adenocarcinoma cell	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
CTP + choline phosphate	-	Homo sapiens	diphosphate + CDPcholine	-	?

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Release 2023.1 (January 2023)