Literature summary for 2.7.7.13 extracted from

Uccelletti, D.; Staneva, D.; Rufini, S.; Venkov, P.; Palleschi, C.
Enhanced secretion of heterologous proteins in Kluyveromyces lactis by overexpression of the GDP-mannose pyrophosphorylase, KlPsa1p (2005), FEMS Yeast Res., 5, 735-746.

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Cloned(Commentary)

Cloned (Comment)	Organism
overexpression reveals changes in cell wall assembly, restores defects in O-glycosylation, but not those in N-glycosylation, that occur in Kluyveromyces lactis cells depleted for the hexokinase Rag5p, overexpression also enhances heterologous protein secretion in Kluyveromyces lactis	Kluyveromyces lactis

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
GTP + alpha-D-mannose 1-phosphate	Kluyveromyces lactis	-	diphosphate + GDP-alpha-D-mannose	-	r

Organism

Organism	UniProt	Comment	Textmining
Kluyveromyces lactis	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
GTP + alpha-D-mannose 1-phosphate	-	Kluyveromyces lactis	diphosphate + GDP-alpha-D-mannose	-	r

Synonyms

Synonyms	Comment	Organism
GDP-mannose pyrophosphorylase	-	Kluyveromyces lactis

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Release 2023.1 (January 2023)