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Literature summary for 2.7.7.105 extracted from

  • Ney, B.; Ahmed, F.; Carere, C.; Biswas, A.; Warden, A.; Morales, S.; Pandey, G.; Watt, S.; Oakeshott, J.; Taylor, M.; Stott, M.; Jackson, C.; Greening, C.
    The methanogenic redox cofactor F420 is widely synthesized by aerobic soil bacteria (2016), ISME J., 11, 125-137 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
gene fbiD, DNA and amino acid sequence determination and analysis, phylogenetic analysis and tree Mycolicibacterium smegmatis
gene fbiD, DNA and amino acid sequence determination and analysis, phylogenetic analysis and tree Thermomicrobium roseum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
phosphoenolpyruvate + GTP Mycolicibacterium smegmatis
-
enolpyruvoyl-2-diphospho-5'-guanosine + diphosphate
-
?
phosphoenolpyruvate + GTP Thermomicrobium roseum
-
enolpyruvoyl-2-diphospho-5'-guanosine + diphosphate
-
?
phosphoenolpyruvate + GTP Thermomicrobium roseum P-2
-
enolpyruvoyl-2-diphospho-5'-guanosine + diphosphate
-
?
phosphoenolpyruvate + GTP Mycolicibacterium smegmatis ATCC 700084
-
enolpyruvoyl-2-diphospho-5'-guanosine + diphosphate
-
?
phosphoenolpyruvate + GTP Thermomicrobium roseum ATCC 27502
-
enolpyruvoyl-2-diphospho-5'-guanosine + diphosphate
-
?
phosphoenolpyruvate + GTP Thermomicrobium roseum DSM 5159
-
enolpyruvoyl-2-diphospho-5'-guanosine + diphosphate
-
?

Organism

Organism UniProt Comment Textmining
Mycolicibacterium smegmatis A0QUZ4
-
-
Mycolicibacterium smegmatis ATCC 700084 A0QUZ4
-
-
Thermomicrobium roseum B9L4T8
-
-
Thermomicrobium roseum ATCC 27502 B9L4T8
-
-
Thermomicrobium roseum DSM 5159 B9L4T8
-
-
Thermomicrobium roseum P-2 B9L4T8
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phosphoenolpyruvate + GTP
-
Mycolicibacterium smegmatis enolpyruvoyl-2-diphospho-5'-guanosine + diphosphate
-
?
phosphoenolpyruvate + GTP
-
Thermomicrobium roseum enolpyruvoyl-2-diphospho-5'-guanosine + diphosphate
-
?
phosphoenolpyruvate + GTP
-
Thermomicrobium roseum P-2 enolpyruvoyl-2-diphospho-5'-guanosine + diphosphate
-
?
phosphoenolpyruvate + GTP
-
Mycolicibacterium smegmatis ATCC 700084 enolpyruvoyl-2-diphospho-5'-guanosine + diphosphate
-
?
phosphoenolpyruvate + GTP
-
Thermomicrobium roseum ATCC 27502 enolpyruvoyl-2-diphospho-5'-guanosine + diphosphate
-
?
phosphoenolpyruvate + GTP
-
Thermomicrobium roseum DSM 5159 enolpyruvoyl-2-diphospho-5'-guanosine + diphosphate
-
?

Synonyms

Synonyms Comment Organism
cofC
-
Mycolicibacterium smegmatis
cofC
-
Thermomicrobium roseum
fbiD
-
Mycolicibacterium smegmatis
fbiD
-
Thermomicrobium roseum

General Information

General Information Comment Organism
evolution analysis of the evolution of the F420 biosynthesis enzymes (CofC, CofD, CofE, CofG and CofH) to understand the origin and distribution of the cofactor, phylogenetic analysis and tree, overview. F420 biosynthesis pathways evolved through bacterial-to-archaeal horizontal gene transfers Mycolicibacterium smegmatis
evolution analysis of the evolution of the F420 biosynthesis enzymes (CofC, CofD, CofE, CofG and CofH) to understand the origin and distribution of the cofactor, phylogenetic analysis and tree, overview. F420 biosynthesis pathways evolved through bacterial-to-archaeal horizontal gene transfers Thermomicrobium roseum