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Literature summary for 2.7.7.101 extracted from

  • Sims, J.; Capon, D.; Dressler, D.
    dnaG (primase)-dependent origins of DNA replication. Nucleotide sequences of the negative strand initiation sites of bacteriophages St-1, phiK, and alpha3 (1979), J. Biol. Chem., 254, 12615-12628 .
    View publication on PubMed
Search for more literature for 2.7.7.101

Organism

Organism UniProt Comment Textmining
Escherichia coli
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
bacteriophage alpha3 ssDNA + n rNTP
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 Escherichia coli bacteriophage alpha3 ssDNA/pppN(pN)n-1 hybrid + (n-1) diphosphate
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bacteriophage G4 ssDNA + n rNTP
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 Escherichia coli bacteriophage G4 ssDNA/pppN(pN)n-1 hybrid + (n-1) diphosphate
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bacteriophage phiK ssDNA + n rNTP
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 Escherichia coli bacteriophage phiK ssDNA/pppN(pN)n-1 hybrid + (n-1) diphosphate
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bacteriophage ST-1 ssDNA + n rNTP
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 Escherichia coli bacteriophage ST-1 ssDNA/pppN(pN)n-1 hybrid + (n-1) diphosphate
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additional information in all four phages studied, the negative strand initiation site occurs within an intercistronic region of approximately 135 bases. Extensive nucleotide conservation exists at the negative strand origin. The conserved origin DNA occurs in two regions, 42 and 45 bases long, which are separated by 13 bases of divergent sequence. The start point of negative strand synthesis lies just prior to one of these hairpins correlated with the two stretches of conserved nucleotide sequence Escherichia coli ?
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