BRENDA - Enzyme Database show
show all sequences of 2.7.6.5

The physiology of stringent factor (ATP:GTP 3-diphosphotransferase) in Escherichia coli

Justesen, J.; Lund, T.; Skou Pedersen, F.; Kjeldgaard, N.O.; Biochimie 68, 715-722 (1986)

Data extracted from this reference:

Activating Compound
Activating Compound
Commentary
Organism
Structure
ethanol
little activity unless activated either by a complex of 70S ribosomes, mRNA and uncharged tRNA or by a solvent like ethanol at approximately 20%
Escherichia coli
additional information
little activity unless activated either by a complex of 70S ribosomes, mRNA and uncharged tRNA or by a solvent like ethanol at approximately 20%
Escherichia coli
mRNA
little activity unless activated either by a complex of 70S ribosomes, mRNA and uncharged tRNA or by a solvent like ethanol at approximately 20%
Escherichia coli
KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
additional information
-
additional information
-
Escherichia coli
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Escherichia coli
-
-
-
Purification (Commentary)
Commentary
Organism
-
Escherichia coli
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ATP + GDP
preferred substrate
642773
Escherichia coli
AMP + guanosine 3'-diphosphate 5'-diphosphate
-
-
-
?
ATP + GTP
-
642773
Escherichia coli
AMP + guanosine 3'-diphosphate 5'-triphosphate
-
-
-
?
Activating Compound (protein specific)
Activating Compound
Commentary
Organism
Structure
ethanol
little activity unless activated either by a complex of 70S ribosomes, mRNA and uncharged tRNA or by a solvent like ethanol at approximately 20%
Escherichia coli
additional information
little activity unless activated either by a complex of 70S ribosomes, mRNA and uncharged tRNA or by a solvent like ethanol at approximately 20%
Escherichia coli
mRNA
little activity unless activated either by a complex of 70S ribosomes, mRNA and uncharged tRNA or by a solvent like ethanol at approximately 20%
Escherichia coli
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
additional information
-
additional information
-
Escherichia coli
Purification (Commentary) (protein specific)
Commentary
Organism
-
Escherichia coli
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ATP + GDP
preferred substrate
642773
Escherichia coli
AMP + guanosine 3'-diphosphate 5'-diphosphate
-
-
-
?
ATP + GTP
-
642773
Escherichia coli
AMP + guanosine 3'-diphosphate 5'-triphosphate
-
-
-
?
Other publictions for EC 2.7.6.5
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
750643
Fernandez-Coll
Contributions of SpoT hydrola ...
Escherichia coli
Front. Microbiol.
9
1802
2018
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1
1
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751808
Honoki
Significance of accumulation ...
Arabidopsis thaliana
Photosyn. Res.
135
299-308
2018
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751910
Gratani
Regulation of the opposing (p ...
Staphylococcus aureus
PLoS Genet.
14
e1007514
2018
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1
1
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737883
Wilkinson
Biochemical studies on Francis ...
Francisella tularensis subsp. tularensis
Biosci. Rep.
35
0000
2015
2
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1
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3
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1
3
1
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4
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1
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1
1
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1
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1
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1
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1
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2
1
1
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1
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1
1
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739546
Steinchen
Catalytic mechanism and allost ...
Bacillus subtilis 168, Bacillus subtilis
Proc. Natl. Acad. Sci. USA
112
13348-13353
2015
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1
1
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5
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1
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8
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6
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1
1
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1
1
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1
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1
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10
1
1
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1
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3
3
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738529
Kriel
GTP dysregulation in Bacillus ...
Bacillus subtilis 168, Bacillus subtilis
J. Bacteriol.
196
189-201
2014
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1
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4
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1
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6
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10
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6
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3
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6
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6
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2
2
6
2
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738524
Weiss
Essential roles for Mycobacter ...
Mycobacterium tuberculosis, Mycobacterium tuberculosis ATCC 25618
J. Bacteriol.
195
5629-5638
2013
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2
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1
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10
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5
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10
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2
2
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722545
Murdeshwar
MS_RHII-RSD, a dual-function R ...
Mycolicibacterium smegmatis, Mycolicibacterium smegmatis mc(2)155 / ATCC 700084
J. Bacteriol.
194
4003-4014
2012
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1
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1
2
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1
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22
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1
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1
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6
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2
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6
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2
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1
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721638
Payoe
Dependence of rela-mediated (p ...
Escherichia coli
Biochemistry
50
3075-3083
2011
1
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1
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674297
Gruendling
Staphylococcus aureus mutants ...
Staphylococcus aureus
J. Bacteriol.
188
6286-6297
2006
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7
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661218
Avarbock
Functional Regulation of the O ...
Mycobacterium tuberculosis
Biochemistry
44
9913-9923
2005
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1
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7
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5
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2
3
1
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2
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661712
Knutsson Jenvert
Characterization of the tRNA a ...
Escherichia coli, Escherichia coli MRE 600
FEBS J.
272
685-695
2005
2
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1
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4
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1
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28
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661439
Hogg
Conformational antagonism betw ...
Streptococcus dysgalactiae
Cell
117
57-68
2004
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1
1
1
2
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1
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2
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642777
Jones
Guanosine pentaphosphate synth ...
Streptomyces antibioticus
J. Bacteriol.
178
4281-4288
1996
1
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1
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3
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1
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1
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1
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642774
Jones
Purification and properties of ...
Saccharopolyspora erythraea, Streptomyces albus, Streptomyces ambofaciens, Streptomyces antibioticus, Streptomyces anulatus, Streptomyces coelicolor, Streptomyces fradiae, Streptomyces fradiae UC8306, Streptomyces glaucescens, Streptomyces glaucescens ETH 22794, Streptomyces lividans, Streptomyces lividans TK24, Streptomyces parvulus
J. Bacteriol.
176
1475-1481
1994
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2
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17
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1
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13
1
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1
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13
1
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642775
Jones
Activation of ATP:GTP 3-pyroph ...
Streptomyces antibioticus
J. Bacteriol.
176
1482-1487
1994
5
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5
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642776
Metzger
The nucleotide sequence and ch ...
Escherichia coli
J. Biol. Chem.
263
15699-15704
1988
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642773
Justesen
The physiology of stringent fa ...
Escherichia coli
Biochimie
68
715-722
1986
3
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642772
Fehr
Stringent response of Bacillus ...
Geobacillus stearothermophilus
J. Bacteriol.
145
68-73
1981
2
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2
2
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642771
Sy
Purification and properties of ...
Brevibacillus brevis
Biochemistry
15
4399-4403
1976
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4
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1
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