Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-Amino-4-hydroxy-6-carboxydihydropteridine | competitive with 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine | Plasmodium chabaudi |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.01 | - |
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine | pH 8.5, 37°C | Plasmodium chabaudi | |
0.011 | - |
ATP | pH 8.5, 37°C | Plasmodium chabaudi |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
190000 | - |
gel filtration | Plasmodium chabaudi |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Plasmodium chabaudi | - |
- |
- |
Purification (Comment) | Organism |
---|---|
partial | Plasmodium chabaudi |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Plasmodium chabaudi |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine | - |
Plasmodium chabaudi | AMP + 2-amino-7,8-dihydro-4-hydroxy-6-(diphosphooxymethyl)pteridine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
7,8-dihydropteroate-synthesizing enzyme | it is not possible to distinguish, whether the enzyme exists as an enzyme complex of 6-hydroxymethyl-7,8-dihydroxypterin pyrophosphokinase and 7,8-dihydropteroate synthase or whether both reactions are catalyzed by a single enzyme | Plasmodium chabaudi |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.7 | - |
- |
Plasmodium chabaudi |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.043 | - |
2-Amino-4-hydroxy-6-carboxydihydropteridine | pH 8.5, 37°C | Plasmodium chabaudi |