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Literature summary for 2.7.6.1 extracted from

  • Jiang, P.; Wei, W.F.; Zhong, G.W.; Zhou, X.G.; Qiao, W.R.; Fisher, R.; Lu, L.
    The function of the three phosphoribosyl pyrophosphate synthetase (Prs) genes in hyphal growth and conidiation in Aspergillus nidulans (2017), Microbiology, 163, 218-232 .
    View publication on PubMed
Search for more literature for 2.7.6.1

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
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 Aspergillus nidulans 5829
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Organism

Organism UniProt Comment Textmining
Aspergillus nidulans
-
-
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Aspergillus nidulans Q5AYB9 isoform PrsA
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Aspergillus nidulans ATCC 38163
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-
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Aspergillus nidulans ATCC 38163 Q5AYB9 isoform PrsA
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Source Tissue

Source Tissue Comment Organism Textmining

Synonyms

Synonyms Comment Organism
AN6711.2
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 Aspergillus nidulans
PrsA
-
 Aspergillus nidulans
PrsB
-
 Aspergillus nidulans
PrsC
-
 Aspergillus nidulans

General Information

General Information Comment Organism
physiological function deletion of PrsA has no detectable effect on cellular morphology compared to that of the parental wild-type strain and PrsA is not required during hyphal elongation Aspergillus nidulans
physiological function genome contains three PRPP synthase-homologous genes (PrsA, PrsB and PrsC).PrsB and PrsC are auxotrophic genes. The mRNA levels of PrsA, prsB and PrsC are dynamic during germination, hyphal growth and sporulation and show abundant expression during the vigorous hyphal growth. Inhibiting the expression of PrsB or prsC produces more effects on the total PRPP synthetase activity than inhibiting PrsA. The constitutive overexpression of PrsA or PrsC can rescue the defective phenotype of the PrsB-absent strain Aspergillus nidulans