Literature summary for 2.7.4.9 extracted from

Chen, Y.L.; Lin, D.W.; Chang, Z.F.
Identification of a putative human mitochondrial thymidine monophosphate kinase associated with monocytic/macrophage terminal differentiation (2008), Genes Cells, 13, 679-689.

Search for more literature for 2.7.4.9

Cloned(Commentary)

Cloned (Comment)	Organism
expression as fusion protein with Green Fluorescent Protein in HeLa cell	Homo sapiens

Protein Variants

Protein Variants	Comment	Organism
additional information	expression as fusion protein with Green Fluorescent Protein in HeLa cell, mitochondrial localization. Over-expression of TMPK2 increases the steady-state level of cellular dTTP and promotes the conversion of radioactive labeled-thymidine and -dTMP to dTDP and dTTP in mitochondria	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
mitochondrion	isoform TMPK2, mitochondrial import sequence at its N-terminus and mitochondrial localization of Green Fluorescent Protein fusion protein	Homo sapiens	5739	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
monocyte	upregulation in monocyte/macrophage differentiating cells	Homo sapiens	-
additional information	expression in several tissues and erythroblastoma cell lines	Homo sapiens	-

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Release 2023.1 (January 2023)