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Literature summary for 2.7.4.8 extracted from

  • Blaszczyk, J.; Li, Y.; Yan, H.; Ji, X.
    Crystal structure of unligated guanylate kinase from yeast reveals GMP-induced conformational changes (2001), J. Mol. Biol., 307, 247-257.
    View publication on PubMed

Crystallization (Commentary)

Crystallization (Comment) Organism
crystal structure of the enzyme with a non-acetylated N terminus in its unligated form as well as in complex with GMP Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae P15454 RCSB Protein Data Bank: 1EX6, enzyme with a non-acetylated N terminus in its unligated form
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Saccharomyces cerevisiae P15454 RCSB Protein Data Bank: 1EX7, enzyme with a non-acetylated N terminus in a complex with GMP
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + GMP GMP binding induces conformational changes in non-acetylated N-terminus mutants Saccharomyces cerevisiae ADP + GDP
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