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Literature summary for 2.7.4.6 extracted from

  • Los Milagros Camara, M.; Bouvier, L.; Reigada, C.; Digirolamo, F.A.; Saye, M.; Pereira, C.A.
    A novel stage-specific glycosomal nucleoside diphosphate kinase from Trypanosoma cruzi (2017), Folia Parasitol., 64, 0006 .
    View publication on PubMed
Search for more literature for 2.7.4.6

Cloned(Commentary)

Cloned (Comment) Organism
cloned and expressed in Escherichia coli Trypanosoma cruzi

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1
-
 dTDP pH and temperature not specified in the publication Trypanosoma cruzi

Localization

Localization Comment Organism GeneOntology No. Textmining
glycosome
-
 Trypanosoma cruzi 20015
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
39300
-
 calculated from sequence Trypanosoma cruzi
41800
-
 SDS-PAGE Trypanosoma cruzi

Organism

Organism UniProt Comment Textmining
Trypanosoma cruzi Q4E256
-
-
Trypanosoma cruzi CL Brener Q4E256
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Trypanosoma cruzi

Source Tissue

Source Tissue Comment Organism Textmining
trypomastigote the isoenzyme form TcNDPK3 is found only in the bloodstream trypomastigotes. TcNDPK3 mRNA is also detected at lower levels in amastigotes suggesting regulation at protein and mRNA level Trypanosoma cruzi
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + dTDP
-
 Trypanosoma cruzi ADP + dTTP
-
 ?
ATP + dTDP
-
 Trypanosoma cruzi CL Brener ADP + dTTP
-
 ?

Subunits

Subunits Comment Organism
? x * 41800, SDS-PAGE Trypanosoma cruzi

Synonyms

Synonyms Comment Organism
TcNDPK3
-
 Trypanosoma cruzi

pI Value

Organism Comment pI Value Maximum pI Value
Trypanosoma cruzi calculated from sequence
-
 5.2