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Literature summary for 2.7.4.6 extracted from

  • Jeudy, S.; Lartigue, A.; Claverie, J.M.; Abergel, C.
    Dissecting the unique nucleotide specificity of mimivirus nucleoside diphosphate kinase (2009), J. Virol., 83, 7142-7150.
    View publication on PubMedView publication on EuropePMC

Crystallization (Commentary)

Crystallization (Comment) Organism
in complex with nucleotides, vapor diffusion method, using 40-45% (v/v) 2-methyl-2,4-pentane-d12-diol in 0.1 M HEPES (pH 7.5) or 0.1 M MOPS (pH 7.4) Acanthamoeba polyphaga Mimivirus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + NDP Acanthamoeba polyphaga Mimivirus
-
ADP + NTP
-
?

Organism

Organism UniProt Comment Textmining
Acanthamoeba polyphaga Mimivirus Q5UQL3
-
-

Purification (Commentary)

Purification (Comment) Organism
HiTrap Ni2+ chelating column chromatography, gel filtration Acanthamoeba polyphaga Mimivirus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + CDP
-
Acanthamoeba polyphaga Mimivirus ADP + CTP
-
?
ATP + dADP
-
Acanthamoeba polyphaga Mimivirus ADP + dATP
-
?
ATP + dCDP
-
Acanthamoeba polyphaga Mimivirus ADP + dCTP
-
?
ATP + dGDP
-
Acanthamoeba polyphaga Mimivirus ADP + dGTP
-
?
ATP + dTDP
-
Acanthamoeba polyphaga Mimivirus ADP + dTTP
-
?
ATP + dUDP
-
Acanthamoeba polyphaga Mimivirus ADP + dUTP
-
?
ATP + NDP
-
Acanthamoeba polyphaga Mimivirus ADP + NTP
-
?
ATP + UDP
-
Acanthamoeba polyphaga Mimivirus ADP + UTP
-
?

Subunits

Subunits Comment Organism
hexamer x-ray crystallography Acanthamoeba polyphaga Mimivirus

Synonyms

Synonyms Comment Organism
NDK
-
Acanthamoeba polyphaga Mimivirus
nucleoside diphosphate kinase
-
Acanthamoeba polyphaga Mimivirus

Cofactor

Cofactor Comment Organism Structure
ATP
-
Acanthamoeba polyphaga Mimivirus