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Literature summary for 2.7.4.6 extracted from

  • Jeudy, S.; Claverie, J.M.; Abergel, C.
    The nucleoside diphosphate kinase from mimivirus: a peculiar affinity for deoxypyrimidine nucleotides (2006), J. Bioenerg. Biomembr., 38, 247-254.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
dCDP minimal inhibitory concentration 0.010 to 0.050mM Acanthamoeba polyphaga Mimivirus
dTDP minimal inhibitory concentration 0.001 mM Acanthamoeba polyphaga Mimivirus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.001
-
dTDP pH 7.5 Acanthamoeba polyphaga Mimivirus
0.005
-
ATP pH 7.5 Acanthamoeba polyphaga Mimivirus
0.01
-
dCDP pH 7.5 Acanthamoeba polyphaga Mimivirus
0.01
-
dUDP pH 7.5 Acanthamoeba polyphaga Mimivirus
0.02
-
dCTP pH 7.5 Acanthamoeba polyphaga Mimivirus
0.025
-
dUTP pH 7.5 Acanthamoeba polyphaga Mimivirus
0.03
-
dTDP pH 7.5 Acanthamoeba polyphaga Mimivirus
0.04
-
CTP pH 7.5 Acanthamoeba polyphaga Mimivirus
0.041
-
dGTP pH 7.5 Acanthamoeba polyphaga Mimivirus
0.05
-
CDP pH 7.5 Acanthamoeba polyphaga Mimivirus
0.1
-
UDP pH 7.5 Acanthamoeba polyphaga Mimivirus
0.11
-
UTP pH 7.5 Acanthamoeba polyphaga Mimivirus
0.14
-
dGDP pH 7.5 Acanthamoeba polyphaga Mimivirus
0.77
-
ADP pH 7.5 Acanthamoeba polyphaga Mimivirus
0.83
-
GTP pH 7.5 Acanthamoeba polyphaga Mimivirus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
112000
-
gel filtration Acanthamoeba polyphaga Mimivirus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Acanthamoeba polyphaga Mimivirus role of enzyme in dUTP detoxification to compensate for the absence of a dUTPase in Mimivirus ?
-
?

Organism

Organism UniProt Comment Textmining
Acanthamoeba polyphaga Mimivirus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ADP + CTP
-
Acanthamoeba polyphaga Mimivirus ATP + CDP
-
?
ADP + dCTP
-
Acanthamoeba polyphaga Mimivirus ATP + dCDP
-
?
ADP + dTTP
-
Acanthamoeba polyphaga Mimivirus ATP + dTDP
-
?
ADP + dUTP
-
Acanthamoeba polyphaga Mimivirus ATP + dUDP
-
?
ADP + GTP
-
Acanthamoeba polyphaga Mimivirus ATP + GDP
-
?
ADP + UTP
-
Acanthamoeba polyphaga Mimivirus ATP + UDP
-
?
ATP + CDP
-
Acanthamoeba polyphaga Mimivirus ADP + CTP
-
?
ATP + dCDP
-
Acanthamoeba polyphaga Mimivirus ADP + dCTP
-
?
ATP + dTDP
-
Acanthamoeba polyphaga Mimivirus ADP + dTTP
-
?
ATP + dUDP
-
Acanthamoeba polyphaga Mimivirus ADP + dUTP
-
?
ATP + GDP
-
Acanthamoeba polyphaga Mimivirus ADP + GTP
-
?
ATP + UDP
-
Acanthamoeba polyphaga Mimivirus ADP + UTP
-
?
dGDP + ATP
-
Acanthamoeba polyphaga Mimivirus dGTP + ADP
-
?
dGTP + ADP
-
Acanthamoeba polyphaga Mimivirus dGDP + ATP
-
?
GTP + ADP
-
Acanthamoeba polyphaga Mimivirus GDP + ATP
-
?
additional information role of enzyme in dUTP detoxification to compensate for the absence of a dUTPase in Mimivirus Acanthamoeba polyphaga Mimivirus ?
-
?
additional information preferential affinity for deoxypyrimidine nucleotides Acanthamoeba polyphaga Mimivirus ?
-
?

Subunits

Subunits Comment Organism
hexamer
-
Acanthamoeba polyphaga Mimivirus