Any feedback?
Literature summary for 2.7.4.6 extracted from
- Membrane-associated nucleoside diphosphate kinase from rat liver. Purification, characterization, and comparison with cytosolic enzyme (1988), J. Biol. Chem., 263, 4647-4653.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.031 | - |
GDP | cosubstrate ATP, cytosolic kinase | Rattus norvegicus |  |
| 0.036 | - |
GDP | cosubstrate ATP, membrane-associated kinase | Rattus norvegicus | |
| 0.042 | - |
ADP | cosubstrate ATP, cytosolic kinase | Rattus norvegicus | |
| 0.073 | - |
ADP | cosubstrate ATP, membrane-associated kinase | Rattus norvegicus | |
| 0.16 | - |
UDP | cosubstrate ATP, membrane-associated kinase | Rattus norvegicus | |
| 0.19 | - |
UDP | cosubstrate ATP, cytosolic kinase | Rattus norvegicus | |
| 0.5 | 0.54 | CDP | cosubstrate ATP | Rattus norvegicus | |
| 0.5 | 0.54 | CDP | cytosolic kinase | Rattus norvegicus | |
| 0.69 | - |
CDP | cosubstrate ATP, membrane-associated kinase | Rattus norvegicus | |
| 1.33 | - |
ATP | cosubstrate GDP, cytosolic kinase | Rattus norvegicus | |
| 1.66 | - |
ATP | cosubstrate GDP, membrane-associated kinase | Rattus norvegicus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytoplasmic membrane | cytosolic and plasma membrane-associated enzymes are quite similar, if not identical | Rattus norvegicus | - |
- |
| cytosol | cytosolic and plasma membrane-associated enzymes are quite similar, if not identical | Rattus norvegicus | 5829 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 99700 | - |
sucrose density gradient centrifugation | Rattus norvegicus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| NDP + NTP | Rattus norvegicus | major component of nucleoside triphosphate synthetic pathway | NTP + NDP | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + ADP | - |
Rattus norvegicus | ADP + ATP | - |
? | |
| ATP + CDP | - |
Rattus norvegicus | ADP + CTP | - |
? | |
| ATP + UDP | - |
Rattus norvegicus | ADP + UTP | - |
? | |
| GTP + ADP | - |
Rattus norvegicus | GDP + ATP | - |
r | |
| NDP + NTP | major component of nucleoside triphosphate synthetic pathway | Rattus norvegicus | NTP + NDP | - |
? | |
| NTP + nucleoside diphosphate | - |
Rattus norvegicus | NDP + NTP | - |
? | |
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