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Literature summary for 2.7.4.6 extracted from

  • Gilles, A.M.; Presecan, E.; Vonica, A.; Lascu, I.
    Nucleoside diphosphate kinase from human erythrocytes. Structural characterization of the two polypeptide chains responsible for heterogeneity of the hexameric enzyme (1991), J. Biol. Chem., 266, 8784-8789.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
8-bromo-IDP in excess Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.033
-
8-bromo-IDP isozyme A6, 25°C Homo sapiens
0.06
-
8-bromo-IDP isozyme B6, 25°C Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Homo sapiens

Renatured (Commentary)

Renatured (Comment) Organism
renaturation of subunit polypeptides A and B generates several isozymes Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
erythrocyte
-
Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
550
-
isozyme A6, 25°C Homo sapiens
740
-
isozyme B6, 25°C Homo sapiens
800
-
native enzyme Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 8-bromo-IDP
-
Homo sapiens ADP + ?
-
?
NTP + nucleoside diphosphate
-
Homo sapiens NDP + NTP
-
?