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Literature summary for 2.7.4.6 extracted from
- Isolation and kinetic studies of nucleoside diphosphokinase from human platelets and effects of cAMP phosphodiesterase inhibitors (1986), Biochem. Pharmacol., 35, 4449-4455.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | no inhibition by papaverine | Homo sapiens | |
| theophylline | - |
Homo sapiens |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.024 | - |
ADP | cosubstrate GTP | Homo sapiens | |
| 0.12 | - |
GTP | cosubstrate ADP | Homo sapiens | |
| 0.2 | 0.38 | ATP | cosubstrate dTDP, two different assays | Homo sapiens | |
| 0.21 | 0.39 | dTDP | cosubstrate ATP, two different assays | Homo sapiens | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 70000 | - |
- |
Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| platelet | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| NTP + nucleoside diphosphate | - |
Homo sapiens | NDP + NTP | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 1700, SDS-PAGE | Homo sapiens |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8 | - |
- |
Homo sapiens |
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