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Literature summary for 2.7.4.34 extracted from

  • Zhang, H.; Ishige, K.; Kornberg, A.
    A polyphosphate kinase (PPK2) widely conserved in bacteria (2002), Proc. Natl. Acad. Sci. USA, 99, 16678-16683 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.4.34

Activating Compound

Activating Compound Comment Organism Structure
Polyphosphate stimulation Pseudomonas aeruginosa

Cloned(Commentary)

Cloned (Comment) Organism
-
 Pseudomonas aeruginosa

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.68
-
 GTP pH 7.2, 37°C Pseudomonas aeruginosa

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ preference for Mn2+ over Mg2+ Pseudomonas aeruginosa
Mn2+ preference for Mn2+ over Mg2+ Pseudomonas aeruginosa

Organism

Organism UniProt Comment Textmining
Pseudomonas aeruginosa Q9I6Z1 cf. EC 2.7.4.1
-
Pseudomonas aeruginosa DSM 22644 Q9I6Z1 cf. EC 2.7.4.1
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GDP + (phosphate)n+1 short polyphosphyate chains are preferred, enzyme displays processivity Pseudomonas aeruginosa GTP + (phosphate)n
-
 r
GDP + (phosphate)n+1 short polyphosphyate chains are preferred, enzyme displays processivity Pseudomonas aeruginosa DSM 22644 GTP + (phosphate)n
-
 r
GTP + (phosphate)n polyphosphate chains of 15-700 are all effective in synthesis, but P3 is not Pseudomonas aeruginosa GDP + (phosphate)n+1
-
 r
additional information the polyphosphate-driven nucleoside diphosphate kinase synthesis of GTP from GDP is 75fold greater than the polyphosphate synthesis from GTP. GTP and ATP are equally active in polyphosphate synthesis Pseudomonas aeruginosa ?
-
-
additional information the polyphosphate-driven nucleoside diphosphate kinase synthesis of GTP from GDP is 75fold greater than the polyphosphate synthesis from GTP. GTP and ATP are equally active in polyphosphate synthesis Pseudomonas aeruginosa DSM 22644 ?
-
-

Subunits

Subunits Comment Organism
? x * 40800, calculated from sequence Pseudomonas aeruginosa

Synonyms

Synonyms Comment Organism
PA0141
-
 Pseudomonas aeruginosa
PPK2
-
 Pseudomonas aeruginosa