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Literature summary for 2.7.4.3 extracted from

  • Font, B.; Gautherson, D.C.
    General and kinetic properties of pig heart mitochondrial adenylate kinase (1980), Biochim. Biophys. Acta, 611, 299-308.
    View publication on PubMed
Search for more literature for 2.7.4.3

Inhibitors

Inhibitors Comment Organism Structure
5,5'-dithiobis(2-nitrobenzoic acid) DTT reverses; not: mitochondrial enzyme Sus scrofa
AMP above 1 mM; substrate inhibition Sus scrofa
P1,P5-diadenosine 5'-pentaphosphate weak Sus scrofa

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol cytosolic and mitochondrial kinases are distinct isozymes Sus scrofa 5829
-
mitochondrion intermembrane space Sus scrofa 5739
-
mitochondrion cytosolic and mitochondrial kinases are distinct isozymes Sus scrofa 5739
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ requirement Sus scrofa

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Sus scrofa

Source Tissue

Source Tissue Comment Organism Textmining
heart
-
 Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ADP + ADP
-
 Sus scrofa ATP + AMP
-
 r
ATP + AMP best substrates Sus scrofa ADP + ADP
-
 r
ATP + AMP highly specific for AMP Sus scrofa ADP + ADP
-
 r
ATP + AMP no substrates are GMP, UMP, CMP Sus scrofa ADP + ADP
-
 r
ATP + AMP less specific for ATP Sus scrofa ADP + ADP
-
 r
CTP + AMP
-
 Sus scrofa ADP + CDP
-
 ?
GTP + AMP
-
 Sus scrofa ADP + GDP
-
 ?
UTP + AMP
-
 Sus scrofa ADP + UDP
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
 assay at Sus scrofa