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Literature summary for 2.7.4.24 extracted from

  • Riley, A.M.; Wang, H.; Weaver, J.D.; Shears, S.B.; Potter, B.V.
    First synthetic analogues of diphosphoinositol polyphosphates: interaction with PP-InsP5 kinase (2012), Chem. Commun. (Camb. ), 48, 11292-11294.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.4.24

Inhibitors

Inhibitors Comment Organism Structure
2-O-benzyl-5-(phosphonoacetic acid ester)-1D-myo-inositol tetrakisphosphate
-
 Homo sapiens
5-(phosphonoacetic acid ester)-1D-myo-inositol pentakisphosphate most potent inhibitor Homo sapiens
5-(phosphonoacetic acid ester)-1D-myo-inositol tetrakisphosphate
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens O43314 isoform PPIP5K2
-

Synonyms

Synonyms Comment Organism
diphosphoinositol pentakisphosphate kinase
-
 Homo sapiens
PP-InsP5 kinase
-
 Homo sapiens
PPIP5K2 isoform Homo sapiens

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.129
-
 pH and temperature not specified in the publication Homo sapiens 5-(phosphonoacetic acid ester)-1D-myo-inositol pentakisphosphate
0.391
-
 pH and temperature not specified in the publication Homo sapiens 2-O-benzyl-5-(phosphonoacetic acid ester)-1D-myo-inositol tetrakisphosphate
1.386
-
 pH and temperature not specified in the publication Homo sapiens 5-(phosphonoacetic acid ester)-1D-myo-inositol tetrakisphosphate