Inhibitors | Comment | Organism | Structure |
---|---|---|---|
5,5'-dithiobis(2-nitrobenzoate) | 0.1 mM, almost complete inactivation after 5 min, phosphomevalonate partially protects, inactivation is reverted by 2-mercaptoethanol or dithiothreitol | Sus scrofa | |
pyridoxal 5'-phosphate | 0.5 mM, 80% inactivation after 30 min, phosphomevalonate protects | Sus scrofa | |
pyridoxamine 5'-phosphate | 0.25 mM, 60% inactivation after 20 min | Sus scrofa |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0082 | - |
phosphomevalonate | pH 7.5, 30°C | Sus scrofa | |
0.256 | - |
ATP | pH 7.5, 30°C | Sus scrofa |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Sus scrofa | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 5-phosphomevalonate | - |
Sus scrofa | ADP + 5-diphosphomevalonate | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | - |
assay at | Sus scrofa |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
10.2 | - |
phosphomevalonate | pH 7.5, 30°C | Sus scrofa |