Literature summary for 2.7.4.15 extracted from

Gigliobianco, T.; Lakaye, B.; Makarchikov, A.F.; Wins, P.; Bettendorff, L.
Adenylate kinase-independent thiamine triphosphate accumulation under severe energy stress in Escherichia coli (2008), BMC Microbiol., 8, 16.

Search for more literature for 2.7.4.15

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	BL21 strain and heat-sensitive CV2, CGSC 4682 strain	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
additional information	-	thiamine triphoshate accumulation in response to amino acid starvation, controverse mechanism of synthesis dicussed, adenylate kinase-independent accumulation of thiamine triphosphate, heat-sensitive CV2 strain of Escherichia coli accumulates thiamine triphosphate despite full inactivation of adenylate cyclase and subsequent decrease of cellular ATP, ATP-dependent mechanisms for thiamine triphosphate synthesis not favoured since large accumulation also observed during energy stress where ATP is low	Escherichia coli

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	enzymatic synthesis of thiamine triphosphate in Escherichia coli	Escherichia coli	?	-	?

Synonyms

Synonyms	Comment	Organism
thiamine diphosphate kinase	-	Escherichia coli

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Release 2023.1 (January 2023)