Cloned (Comment) | Organism |
---|---|
DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic tree | Amphibalanus amphitrite |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
quercetin | - |
Amphibalanus amphitrite | |
rutin | - |
Amphibalanus amphitrite |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required | Amphibalanus amphitrite |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
40000 | - |
x * 40000, about, sequence calculation | Amphibalanus amphitrite |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + L-arginine | Amphibalanus amphitrite | specific reversible transfer of phosphate | ADP + Nomega-phospho-L-arginine | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Amphibalanus amphitrite | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
larva | among the developmental stages, the enzyme is highly expressed during the cyprid stage. Along with the aging process in cyprids, the level of enzyme decreases | Amphibalanus amphitrite | - |
muscle | the enzyme is localized to muscular tissues in cyprids, including antennules, antennular muscles, and thoracic limbs | Amphibalanus amphitrite | - |
nauplius | nauplius VI larval stage, the enzyme is round the compound eye, the thoraco-abdomen, antennules, and under the dorsal shield | Amphibalanus amphitrite | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + L-arginine | specific reversible transfer of phosphate | Amphibalanus amphitrite | ADP + Nomega-phospho-L-arginine | - |
r |
Subunits | Comment | Organism |
---|---|---|
? | x * 40000, about, sequence calculation | Amphibalanus amphitrite |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ADP | - |
Amphibalanus amphitrite | |
ATP | - |
Amphibalanus amphitrite |
Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|
Amphibalanus amphitrite | sequence calculation | - |
5.98 |
Organism | Comment | Expression |
---|---|---|
Amphibalanus amphitrite | in response to SB203580 treatments, the expression level of enzyme is decreased in cyprids, as well as in response to treatment with two NOS inhibitors, S-methylisothiourea sulfate and aminoguanidine hemisulfate, or guanylyl cyclase inhibitor 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one | down |
Amphibalanus amphitrite | sodium nitroprusside treatment gradually increases the expression of the enzyme | up |
General Information | Comment | Organism |
---|---|---|
evolution | the enzyme is widely distributed in various invertebrates and many lower chordates but absent in vertebrates | Amphibalanus amphitrite |
malfunction | larval settlement rate decreases and larval movement is inhibited in response to treatments with high concentrations of enzyme inhibitors rutin and quercetin | Amphibalanus amphitrite |
metabolism | arginine kinase mainly participates in energy metabolism in invertebrates. Arginine kinase is functionally analogous to creatine kinase, EC 2.7.3.2, in vertebrates | Amphibalanus amphitrite |
physiological function | the enzyme is involved in the larval settlement through mediating energy supply in muscle tissues. The enzyme mainly provides energy for muscle movements and is essential for motility in arthropods | Amphibalanus amphitrite |