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Literature summary for 2.7.3.3 extracted from

  • Zhang, G.; Yan, G.; Yang, X.; Wong, Y.; Sun, J.; Zhang, Y.; He, L.; Xu, Y.; Qian, P.
    Characterization of arginine kinase in the barnacle Amphibalanus amphitrite and its role in the larval settlement (2016), J. Exp. Zool. B, 326, 237-249.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic tree Amphibalanus amphitrite

Inhibitors

Inhibitors Comment Organism Structure
quercetin
-
Amphibalanus amphitrite
rutin
-
Amphibalanus amphitrite

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required Amphibalanus amphitrite

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
40000
-
x * 40000, about, sequence calculation Amphibalanus amphitrite

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + L-arginine Amphibalanus amphitrite specific reversible transfer of phosphate ADP + Nomega-phospho-L-arginine
-
r

Organism

Organism UniProt Comment Textmining
Amphibalanus amphitrite
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
larva among the developmental stages, the enzyme is highly expressed during the cyprid stage. Along with the aging process in cyprids, the level of enzyme decreases Amphibalanus amphitrite
-
muscle the enzyme is localized to muscular tissues in cyprids, including antennules, antennular muscles, and thoracic limbs Amphibalanus amphitrite
-
nauplius nauplius VI larval stage, the enzyme is round the compound eye, the thoraco-abdomen, antennules, and under the dorsal shield Amphibalanus amphitrite
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-arginine specific reversible transfer of phosphate Amphibalanus amphitrite ADP + Nomega-phospho-L-arginine
-
r

Subunits

Subunits Comment Organism
? x * 40000, about, sequence calculation Amphibalanus amphitrite

Cofactor

Cofactor Comment Organism Structure
ADP
-
Amphibalanus amphitrite
ATP
-
Amphibalanus amphitrite

pI Value

Organism Comment pI Value Maximum pI Value
Amphibalanus amphitrite sequence calculation
-
5.98

Expression

Organism Comment Expression
Amphibalanus amphitrite in response to SB203580 treatments, the expression level of enzyme is decreased in cyprids, as well as in response to treatment with two NOS inhibitors, S-methylisothiourea sulfate and aminoguanidine hemisulfate, or guanylyl cyclase inhibitor 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one down
Amphibalanus amphitrite sodium nitroprusside treatment gradually increases the expression of the enzyme up

General Information

General Information Comment Organism
evolution the enzyme is widely distributed in various invertebrates and many lower chordates but absent in vertebrates Amphibalanus amphitrite
malfunction larval settlement rate decreases and larval movement is inhibited in response to treatments with high concentrations of enzyme inhibitors rutin and quercetin Amphibalanus amphitrite
metabolism arginine kinase mainly participates in energy metabolism in invertebrates. Arginine kinase is functionally analogous to creatine kinase, EC 2.7.3.2, in vertebrates Amphibalanus amphitrite
physiological function the enzyme is involved in the larval settlement through mediating energy supply in muscle tissues. The enzyme mainly provides energy for muscle movements and is essential for motility in arthropods Amphibalanus amphitrite