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Literature summary for 2.7.3.3 extracted from

  • Wu, X.Q.; Zhu, W.J.; Lue, Z.R.; Xia, Y.; Yang, J.M.; Zou, F.; Wang, X.Y.
    The effect of rutin on arginine kinase: inhibition kinetics and thermodynamics merging with docking simulation (2009), Int. J. Biol. Macromol., 44, 149-155.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
rutin noncompetitive inhibitor, i.e. 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one, about 20% residual activity at 0.02-0.06 mM rutin Locusta migratoria

Organism

Organism UniProt Comment Textmining
Locusta migratoria
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
muscle
-
Locusta migratoria
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-Arg
-
Locusta migratoria ADP + Nomega-phospho-L-Arg
-
?

Synonyms

Synonyms Comment Organism
AK: L-arginine phosphotransferase
-
Locusta migratoria

Cofactor

Cofactor Comment Organism Structure
ATP
-
Locusta migratoria

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.008
-
rutin
-
Locusta migratoria