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Literature summary for 2.7.2.3 extracted from

  • Prasanth, K.R.; Chuang, C.; Nagy, P.D.
    Co-opting ATP-generating glycolytic enzyme PGK1 phosphoglycerate kinase facilitates the assembly of viral replicase complexes (2017), PLoS Pathog., 13, e1006689 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.2.3

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Saccharomyces cerevisiae Nicotiana benthamiana

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Nicotiana benthamiana 5829
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ADP + 3-phospho-D-glyceroyl phosphate Nicotiana benthamiana
-
 ATP + 3-phospho-D-glycerate
-
 r
ATP + 3-phospho-D-glycerate Nicotiana benthamiana
-
 ADP + 3-phospho-D-glyceroyl phosphate
-
 r

Organism

Organism UniProt Comment Textmining
Nicotiana benthamiana E5LLE7
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ADP + 3-phospho-D-glyceroyl phosphate
-
 Nicotiana benthamiana ATP + 3-phospho-D-glycerate
-
 r
ATP + 3-phospho-D-glycerate
-
 Nicotiana benthamiana ADP + 3-phospho-D-glyceroyl phosphate
-
 r

Synonyms

Synonyms Comment Organism
PGK1
-
 Nicotiana benthamiana

General Information

General Information Comment Organism
metabolism the enzyme acts as a pro-viral host factor. Tomato bushy stunt virus co-opts the glycolytic ATP-generating phosphoglycerate kinase 1 to facilitate the intracellular assembly of new viral replicase complexes Nicotiana benthamiana