Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
3-phosphoglycerate kinase | - |
Homo sapiens |
PGK | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
additional information | indispensable for the phosphoryl transfer reaction is a large conformational change from an inactive open to an active closed conformation via a hinge motion that should bring substrates into close proximity, molecular dynamics simulations, network-like representation of significant changes in inter-atomic forces, hydrogen-bond network in hinge bending region of apo and complexed hPGK, overview | Homo sapiens |
physiological function | 3-phosphogycerate kinase is a two domain enzyme, which transfers a phosphate group between its two substrates, 1,3-bisphosphoglycerate bound to the N-domain and ADP bound to the C-domain | Homo sapiens |