Activating Compound | Comment | Organism | Structure |
---|---|---|---|
ethanolamine | induces a 15fold increase in the rate of autophosphorylation in vitro of the HK17 sensor histidine kinase | Enterococcus faecalis |
Cloned (Comment) | Organism |
---|---|
cloning of the RR-HK17 TCS system from strain V583 | Enterococcus faecalis |
Protein Variants | Comment | Organism |
---|---|---|
additional information | ethanolamine utilization and growth on it is abolished in the response regulator RR17 mutant strain lacking a functional partner of histidine kinase in the RR-HK17 two-component system, phenotype, overview | Enterococcus faecalis |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | - |
Enterococcus faecalis | 5737 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | - |
Enterococcus faecalis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Enterococcus faecalis | the sensory histidine kinase acts in the two-component system with the response regulator as RR-HK17, EF1633-EF1632, in the regulation of ethanolamine utilization, which can be the sole carbon source for the organism, mechanism, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Enterococcus faecalis | - |
human clinical isolate | - |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | the enzyme HK17 performs autophosphorylation stimulated by ethanolamine | Enterococcus faecalis |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the sensory histidine kinase acts in the two-component system with the response regulator as RR-HK17, EF1633-EF1632, in the regulation of ethanolamine utilization, which can be the sole carbon source for the organism, mechanism, overview | Enterococcus faecalis | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | the N-terminus of HK17 forms a GAF domain, structure of the RR-HK17 two-component system | Enterococcus faecalis |
Synonyms | Comment | Organism |
---|---|---|
HK17 | - |
Enterococcus faecalis |
sensory histidine kinase | - |
Enterococcus faecalis |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
22 | - |
assay at room temperature | Enterococcus faecalis |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Enterococcus faecalis |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Enterococcus faecalis |