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Literature summary for 2.7.13.3 extracted from

  • Del Papa, M.F.; Perego, M.
    Ethanolamine activates a sensor histidine kinase regulating its utilization in Enterococcus faecalis (2008), J. Bacteriol., 190, 7147-7156.
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
ethanolamine induces a 15fold increase in the rate of autophosphorylation in vitro of the HK17 sensor histidine kinase Enterococcus faecalis

Cloned(Commentary)

Cloned (Comment) Organism
cloning of the RR-HK17 TCS system from strain V583 Enterococcus faecalis

Protein Variants

Protein Variants Comment Organism
additional information ethanolamine utilization and growth on it is abolished in the response regulator RR17 mutant strain lacking a functional partner of histidine kinase in the RR-HK17 two-component system, phenotype, overview Enterococcus faecalis

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
Enterococcus faecalis 5737
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
Enterococcus faecalis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Enterococcus faecalis the sensory histidine kinase acts in the two-component system with the response regulator as RR-HK17, EF1633-EF1632, in the regulation of ethanolamine utilization, which can be the sole carbon source for the organism, mechanism, overview ?
-
?

Organism

Organism UniProt Comment Textmining
Enterococcus faecalis
-
human clinical isolate
-

Posttranslational Modification

Posttranslational Modification Comment Organism
phosphoprotein the enzyme HK17 performs autophosphorylation stimulated by ethanolamine Enterococcus faecalis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the sensory histidine kinase acts in the two-component system with the response regulator as RR-HK17, EF1633-EF1632, in the regulation of ethanolamine utilization, which can be the sole carbon source for the organism, mechanism, overview Enterococcus faecalis ?
-
?

Subunits

Subunits Comment Organism
More the N-terminus of HK17 forms a GAF domain, structure of the RR-HK17 two-component system Enterococcus faecalis

Synonyms

Synonyms Comment Organism
HK17
-
Enterococcus faecalis
sensory histidine kinase
-
Enterococcus faecalis

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
22
-
assay at room temperature Enterococcus faecalis

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
assay at Enterococcus faecalis

Cofactor

Cofactor Comment Organism Structure
ATP
-
Enterococcus faecalis