Literature summary for 2.7.13.3 extracted from

Hallez, R.; Mignolet, J.; Van Mullem, V.; Wery, M.; Vandenhaute, J.; Letesson, J.; Jacobs-Wagner, C.; De Bolle, X.
The asymmetric distribution of the essential histidine kinase PdhS indicates a differentiation event in Brucella abortus (2007), EMBO J., 26, 1444-1455.

Search for more literature for 2.7.13.3

Application

Application	Comment	Organism
additional information	PdhS contains an N-terminal multimerization part and a C-terminal histidine kinase part interacting with DivK, PdhS can enhance the phosphorylation of DivK and its subsequent polar localization, the enzyme has essential functions in controlling some aspects of the division process, maybe through the control of CtrA activity, PdhS recognizes a polar structure conserved in several alpha-proteobacteria	Brucella abortus

Cloned(Commentary)

Cloned (Comment)	Organism
low-copy plasmid pRH324 expressing Brucella abortus pdhS fused to cfp into Sinorhizobium meliloti or Caulobacter crescentus	Brucella abortus

Protein Variants

Protein Variants	Comment	Organism
additional information	deletion of the pdhS in the presence of a rescue copy expressed from pRH232, pRH232 is replaced in the deltapdhS strain only in the presence of another wild-type copy of pdhS through pRH404	Brucella abortus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cytoplasm	is localized at the old pole of the large cell, after division and growth, the small cell acquires PdhS at its old pole, polar localization of PdhS is maintained during a cellular infection by bovine macrophages	Brucella abortus	5737	-

Organism

Organism	UniProt	Comment	Textmining
Brucella abortus	-	all strains derived from Brucella abortus 544 NalR, XDB1104 strain	-
Brucella abortus XDB1104	-	all strains derived from Brucella abortus 544 NalR, XDB1104 strain	-

Synonyms

Synonyms	Comment	Organism
histidine kinase	-	Brucella abortus
PdhS	-	Brucella abortus
PleC-DivJ homolog sensor	-	Brucella abortus

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Release 2023.1 (January 2023)