Activating Compound | Comment | Organism | Structure |
---|---|---|---|
doxycycline | induces expression of HA-MEK1 | Homo sapiens |
Application | Comment | Organism |
---|---|---|
additional information | MEK1 plays an in vivo role in Golgi reorganization, which regulates cell cycle progression, MEK signaling promotes G2/M cell cycle transition by unlinking the Golgi, that involves, at least in part, phosphorylation of the putative Golgi structural protein GRASP55 | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
HA-MEK1 cloned into pRevTRE, HA-tagged MEK1 expressed in HeLa cells | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
siRNA | MEK1/2-specific inhibitor, delays, but does not block the passage of synchronized HeLa cells into M phase | Homo sapiens | |
U0126 | MEK1/2-specific inhibitor, delays, but does not block the passage of synchronized HeLa cells into M phase | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
MEK1 | - |
Homo sapiens |
MEK2 | - |
Homo sapiens |
mitogen-activated protein kinase kinase 1 | - |
Homo sapiens |