Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Mus musculus | 5829 | - |
mitochondrion | localizes to mitochondrial RNA granules | Mus musculus | 5739 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
50000 | - |
- |
Mus musculus |
60000 | - |
- |
Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + [Fas-activated serine/threonine protein] | Mus musculus | - |
ADP + [Fas-activated serine/threonine phosphoprotein] | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Mus musculus | Q9JIX9 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
143B cell | - |
Mus musculus | - |
MEF cell | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + [Fas-activated serine/threonine protein] | - |
Mus musculus | ADP + [Fas-activated serine/threonine phosphoprotein] | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 50000, mitochondrial isoform, SDS-PAGE | Mus musculus |
? | x * 60000, cytosolic isoform, SDS-PAGE | Mus musculus |
Synonyms | Comment | Organism |
---|---|---|
FASTK | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | ablating enzyme expression in cultured cells and mice results specifically in loss of ND6 mRNA and reduced complex I activity in vivo | Mus musculus |
physiological function | the mitochondrial isoform is essential for ND6 mRNA biogenesis and complex I activity | Mus musculus |