Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.11.7 extracted from

  • Ye, Q.; Yang, Y.; van Staalduinen, L.; Crawley, S.W.; Liu, L.; Brennan, S.; Cote, G.P.; Jia, Z.
    Structure of the Dictyostelium myosin-II heavy chain kinase A (MHCK-A) alpha-kinase domain apoenzyme reveals a novel autoinhibited conformation (2016), Sci. Rep., 6, 26634.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.11.7

Cloned(Commentary)

Cloned (Comment) Organism
-
 Dictyostelium discoideum

Crystallization (Commentary)

Crystallization (Comment) Organism
alpha-kinase domain of myosin-II heavy chain kinase A, hanging drop vapor diffusion method, using 5% PEG (w/v) 8000, 20% (w/v) PEG 300, 10% (v/v) glycerol and 0.1 M Tris-HCl, pH 9.0 Dictyostelium discoideum

Protein Variants

Protein Variants Comment Organism
D663A inactive Dictyostelium discoideum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + [myosin II heavy-chain] Dictyostelium discoideum
-
 ADP + [myosin II heavy-chain] phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Dictyostelium discoideum P42527
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Dictyostelium discoideum

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + myelin basic protein
-
 Dictyostelium discoideum ?
-
 ?
ATP + [myosin II heavy-chain]
-
 Dictyostelium discoideum ADP + [myosin II heavy-chain] phosphate
-
 ?

Synonyms

Synonyms Comment Organism
A-CAT alpha-kinase domain of myosin-II heavy chain kinase A Dictyostelium discoideum
MHCK-A
-
 Dictyostelium discoideum
myosin-II heavy chain kinase A
-
 Dictyostelium discoideum