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Literature summary for 2.7.11.5 extracted from
- The reversible phosphorylation of isocitrate dehydrogenase of Salmonella typhimurium (1982), Arch. Biochem. Biophys., 218, 59-67.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| 2-deoxy-D-glucose | - |
Salmonella enterica subsp. enterica serovar Typhimurium |  |
| acetate | - |
Salmonella enterica subsp. enterica serovar Typhimurium | |
| alpha-methylglucoside | - |
Salmonella enterica subsp. enterica serovar Typhimurium | |
| ethanol | - |
Salmonella enterica subsp. enterica serovar Typhimurium | |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| glyoxylate | in combination with oxaloacetate | Salmonella enterica subsp. enterica serovar Typhimurium | |
| oxaloacetate | - |
Salmonella enterica subsp. enterica serovar Typhimurium | |
| pyruvate | - |
Salmonella enterica subsp. enterica serovar Typhimurium | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + [isocitrate dehydrogenase (NADP+)] | Salmonella enterica subsp. enterica serovar Typhimurium | reversible phosphorylation of isocitrate dehydrogenase plays a major role in the control of the Krebs cycle and glyoxylate pathways | ADP + [isocitrate dehydrogenase (NADP+)] phosphate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Salmonella enterica subsp. enterica serovar Typhimurium | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + [isocitrate dehydrogenase (NADP+)] | - |
Salmonella enterica subsp. enterica serovar Typhimurium | ADP + [isocitrate dehydrogenase (NADP+)] phosphate | - |
? | |
| ATP + [isocitrate dehydrogenase (NADP+)] | reversible phosphorylation of isocitrate dehydrogenase plays a major role in the control of the Krebs cycle and glyoxylate pathways | Salmonella enterica subsp. enterica serovar Typhimurium | ADP + [isocitrate dehydrogenase (NADP+)] phosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| IDH kinase | - |
Salmonella enterica subsp. enterica serovar Typhimurium |
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Release 2023.1 (January 2023)
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