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Literature summary for 2.7.11.31 extracted from

  • Woods, A.; Cheung, P.C.; Smith, F.C.; Davison, M.D.; Scott, J.; Beri, R.K.; Carling, D.
    Characterization of AMP-activated protein kinase beta and gamma subunits. Assembly of the heterotrimeric complex in vitro (1996), J. Biol. Chem., 271, 10282-10290.
    View publication on PubMed
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Activating Compound

Activating Compound Comment Organism Structure
5'-AMP
-
 Rattus norvegicus

Cloned(Commentary)

Cloned (Comment) Organism
sequence analysis of cDNA clones encoding the subunits Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
30000
-
 beta-subunit, predicted protein sequence Rattus norvegicus
36000
-
 1 * 63000 * ? + 1 * 38000 + 1 * 36000, alpha, beta, gamma, SDS-PAGE Rattus norvegicus
38000
-
 1 * 63000 * ? + 1 * 38000 + 1 * 36000, alpha, beta, gamma, SDS-PAGE Rattus norvegicus
63000
-
 1 * 63000 * ? + 1 * 38000 + 1 * 36000, alpha, beta, gamma, SDS-PAGE Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + [hydroxymethylglutaryl-CoA reductase (NADPH)]
-
 Rattus norvegicus ADP + [hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate
-
 ?

Subunits

Subunits Comment Organism
heterotrimer 1 * 63000 * ? + 1 * 38000 + 1 * 36000, alpha, beta, gamma, SDS-PAGE Rattus norvegicus