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Literature summary for 2.7.11.31 extracted from

  • Wang, W.; Fan, J.; Yang, X.; Furer-Galban, S.; Lopez de Silanes, I.; von Kobbe, C.; Guo, J.; Georas, S.N.; Foufelle, F.; Hardie, D.G.; Carling, D.; Gorospe, M.
    AMP-activated kinase regulates cytoplasmic HuR (2002), Mol. Cell. Biol., 22, 3425-3436.
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
5'-AMP
-
Homo sapiens

Protein Variants

Protein Variants Comment Organism
S182A site-directed mutagenesis, no effect on enzyme activity Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
Homo sapiens 5737
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
human
-
Homo sapiens
-
colorectal carcinoma RKO cells
-

Source Tissue

Source Tissue Comment Organism Textmining
RKO cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + RNA-binding protein HUR inhibits the protein by phosphorylation Homo sapiens ADP + ?
-
?