Literature summary for 2.7.11.27 extracted from

Zang, M.; Zuccollo, A.; Hou, X.; Nagata, D.; Walsh, K.; Herscovitz, H.; Brecher, P.; Ruderman, N.B.; Cohen, R.A.
AMP-activated protein kinase is required for the lipid-lowering effect of metformin in insulin-resistant human HepG2 cells (2004), J. Biol. Chem., 279, 47898-47905.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + [acetyl-CoA carboxylase]	Homo sapiens	AMPKalpha negatively regulates activity of acetyl-CoA carboxylase and hepatic lipid content	ADP + [acetyl-CoA carboxylase] phosphate	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + [acetyl-CoA carboxylase]	-	Homo sapiens	ADP + [acetyl-CoA carboxylase] phosphate	-	?
ATP + [acetyl-CoA carboxylase]	AMPKalpha negatively regulates activity of acetyl-CoA carboxylase and hepatic lipid content	Homo sapiens	ADP + [acetyl-CoA carboxylase] phosphate	-	?

Synonyms

Synonyms	Comment	Organism
AMPKalpha	-	Homo sapiens

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Release 2023.1 (January 2023)