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Literature summary for 2.7.11.26 extracted from

  • Sul, D.; Kim, H.S.; Lee, D.; Joo, S.S.; Hwang, K.W.; Park, S.Y.
    Protective effect of caffeic acid against beta-amyloid-induced neurotoxicity by the inhibition of calcium influx and tau phosphorylation (2009), Life Sci., 84, 257-262.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
beta-amyloid peptide
-
Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
caffeic acid 0.02 mg/ml caffeic acid decreases the activating phosphorylation of GSK-3beta Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
phosphoprotein
-
Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
PC-12 cell
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + protein tau
-
Rattus norvegicus ADP + protein tau phosphate
-
?

Synonyms

Synonyms Comment Organism
glycogen synthase kinase-3beta
-
Rattus norvegicus
GSK-3beta
-
Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
ATP
-
Rattus norvegicus