Protein Variants | Comment | Organism |
---|---|---|
additional information | generation of the T-DNA insertion lines mpk6-2 (Salk 073907) and mpk6-3(Salk 127507), that are loss-of-function mutants, the mutants are less sensitive to NaCl or Na-glutamate, but not to KCl or mannitol, as compared with that of wild-type seedlings | Arabidopsis thaliana |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
plasma membrane | - |
Arabidopsis thaliana | 5886 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arabidopsis thaliana | Q39026 | - |
- |
Arabidopsis thaliana Col-0 | Q39026 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
root | - |
Arabidopsis thaliana | - |
seedling | - |
Arabidopsis thaliana | - |
Synonyms | Comment | Organism |
---|---|---|
At2g43790 | - |
Arabidopsis thaliana |
mitogen-activated protein kinase 6 | - |
Arabidopsis thaliana |
MPK6 | - |
Arabidopsis thaliana |
General Information | Comment | Organism |
---|---|---|
malfunction | root elongation in seedlings of the loss-of-function mutants mpk6-2 and mpk6-3 is less sensitive to NaCl or Na-glutamate, but not to KCl or mannitol, as compared with that of wild-type seedlings. The tolerance of mpk6 to Na+ toxicity is Ca2+-dependent. At the plasma membrane, increased concentrations of NaCl increase the inward Na+-conducted currents while decreasing the outward Na+-conducted currents in wild-type root cells, attended by a positive shift in membrane potential. In mpk6 mutant root cells, NaCl significantly increases outward but not inward Na+-conducted currents, accompanied by a negative shift in membrane potential. Mutant mpk6 decreases NaCl-induced the Na+ accumulation by modifying PM Na+ flux in root cells. Mutant mpk6 accumulates less Na+ in response to NaCl because of the increased cytosolic Ca2+ level in root cells; thus, its root elongation is less inhibited than that of WT by NaCl | Arabidopsis thaliana |
physiological function | mitogen-activated protein kinase 6 controls root growth in Arabidopsis thaliana by modulating Ca2+-based Na+ flux in root cell under salt stress | Arabidopsis thaliana |