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Literature summary for 2.7.11.24 extracted from

  • da Costa, S.V.; Roela, R.A.; Junqueira, M.S.; Arantes, C.; Brentani, M.M.
    The role of p38 mitogen-activated protein kinase in serum-induced leukemia inhibitory factor secretion by bone marrow stromal cells from pediatric myelodysplastic syndromes (2010), Leuk. Res., 34, 507-512.
    View publication on PubMed
Search for more literature for 2.7.11.24

Application

Application Comment Organism
medicine the study suggests the possible importance in pediatric myelodysplastic syndrome of p38MAPK signaling pathway which may be a future therapeutic target Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
SB203580
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + a protein Homo sapiens
-
 ADP + a phosphoprotein
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
bone marrow
-
 Homo sapiens
-
bone marrow stromal cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + a protein
-
 Homo sapiens ADP + a phosphoprotein
-
 ?

Synonyms

Synonyms Comment Organism
p38 mitogen-activated protein kinase
-
 Homo sapiens
p38MAPK
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Homo sapiens