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Literature summary for 2.7.11.24 extracted from
- Heavy metal stress. Activation of distinct mitogen-activated protein kinase pathways by copper and cadmium (2004), Plant Physiol., 136, 3276-3283.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| additional information | some heavy metals induce MAPK pathways in the plant | Medicago sativa |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| protoplast | - |
Medicago sativa | - |
- |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Cd2+ | causes delayed but strong activation of SIMK, MMK2, MMK3, and SAMK, activation profiles, overview | Medicago sativa |  |
| Cu2+ | strongly activates the MAPK signaling pathways of SIMK, MMK2, MMK3, and SAMK, mediated by the MAPKK SIMKK, activation profiles, overview | Medicago sativa | |
| Fe2+ | activates MMK2, slight induction of SIMK | Medicago sativa | |
| additional information | SIMK activity is not or poorly influenced by Al3+, Zn2+, or Co2+ | Medicago sativa | |
| Pb2+ | slight induction of SIMK | Medicago sativa | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 44000 | - |
x * 44000, MAPKS MMK2, MMK3, and SAMK, SDS-PAGE, x * 46000, SIMK, SDS-PAGE | Medicago sativa |
| 46000 | - |
x * 44000, MAPKS MMK2, MMK3, and SAMK, SDS-PAGE, x * 46000, SIMK, SDS-PAGE | Medicago sativa |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Medicago sativa | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| phosphoprotein | MAPKs are activated by phosphorylation through MAPK kinases, e.g. SIMKK mediates activation of SIMK and SAMK, not of MMK2 and MMK3, by Cu2+, not by Cd2+, no activation of MAPKs SIMK, SAMK, MMK2 and MMK3 by MAPKKs MEK1 and PRKK | Medicago sativa |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| root | - |
Medicago sativa | - |
| seedling | - |
Medicago sativa | - |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 44000, MAPKS MMK2, MMK3, and SAMK, SDS-PAGE, x * 46000, SIMK, SDS-PAGE | Medicago sativa |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| MAPK | - |
Medicago sativa |
| MMK2 | - |
Medicago sativa |
| MMK3 | - |
Medicago sativa |
| SAMK | - |
Medicago sativa |
| SIMK | - |
Medicago sativa |
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