Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | mechanism of p38 MAP kinase activation in vivo, coordinated and selective actions of protein kinases MKK3, MKK4, and MKK6 in response to cytokines and exposure to environmental stress are part of the regulation, overview | Mus musculus | |
TNF-alpha | activates p38 MAPK mediated by protein kinases MKK3, MKK4, and MKK6, overview | Mus musculus | |
UV radiation | activates p38 MAPK mediated by protein kinases, overview | Mus musculus |
Protein Variants | Comment | Organism |
---|---|---|
additional information | enzyme-deficient mutant mice show defects in growth arrest and increased tumorigenesis | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mus musculus | regulation mechanism of p38 MAPK activity involving the protein kinases MKK3, MKK4, and MKK6, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
fibroblast | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | regulation mechanism of p38 MAPK activity involving the protein kinases MKK3, MKK4, and MKK6, overview | Mus musculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
p38 MAP kinase | - |
Mus musculus |
p38 MAPK | - |
Mus musculus |