Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.11.23 extracted from

  • Bennett, C.B.; Westmoreland, T.J.; Verrier, C.S.; Blanchette, C.A.; Sabin, T.L.; Phatnani, H.P.; Mishina, Y.V.; Huper, G.; Selim, A.L.; Madison, E.R.; Bailey, D.D.; Falae, A.I.; Galli, A.; Olson, J.A.; Greenleaf, A.L.; Marks, J.R.
    Yeast screens identify the RNA polymerase II CTD and SPT5 as relevant targets of BRCA1 interaction (2008), PLoS ONE, 3, e1448.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.11.23

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + RNA polymerase II carboxy terminal domain Saccharomyces cerevisiae the phosphorylated RNAPII CTD, interacts with BRCA1 for induction of DEF1-dependent cleavage and accumulation of a RNAPII fragment containing the P-CTD, overview ADP + phosphorylated RNA polymerase II carboxy terminal domain
-
 ?
additional information Saccharomyces cerevisiae CTK1 kinase is required for BRCA1-induced lethality in yeast, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + RNA polymerase II carboxy terminal domain the phosphorylated RNAPII CTD, interacts with BRCA1 for induction of DEF1-dependent cleavage and accumulation of a RNAPII fragment containing the P-CTD, overview Saccharomyces cerevisiae ADP + phosphorylated RNA polymerase II carboxy terminal domain
-
 ?
ATP + RNA polymerase II carboxy terminal domain i.e. RNAPII CTD Saccharomyces cerevisiae ADP + phosphorylated RNA polymerase II carboxy terminal domain
-
 ?
additional information CTK1 kinase is required for BRCA1-induced lethality in yeast, overview Saccharomyces cerevisiae ?
-
 ?

Synonyms

Synonyms Comment Organism
CTDK-I
-
 Saccharomyces cerevisiae
CTDK-I kinase
-
 Saccharomyces cerevisiae

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Saccharomyces cerevisiae