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Literature summary for 2.7.11.23 extracted from
- Phosphorylation of numatrin and other nuclear proteins by cdc2 containing CTD kinase cdc2/p58 (1991), J. Biol. Chem., 266, 16200-16206.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + [DNA-directed eukaryotic RNA polymerase II subunit IIa] | Mus musculus | - |
ADP + phospho-[DNA-directed RNA polymerase II subunit IIa] | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| cell culture | - |
Mus musculus | - |
| Ehrlich ascites carcinoma cell | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + chicken myosin regulatory light-chain | - |
Mus musculus | ADP + chicken myosin regulatory light-chain phosphate | - |
? | |
| ATP + histone H1 | - |
Mus musculus | ADP + phosphohistone H1 | - |
? | |
| ATP + numatrin | and other nuclear proteins | Mus musculus | ADP + phosphonumatrin | - |
? | |
| ATP + [DNA-directed eukaryotic RNA polymerase II subunit IIa] | - |
Mus musculus | ADP + phospho-[DNA-directed RNA polymerase II subunit IIa] | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| More | enzymes from mouse consist of 2 components each: cdc2/p58: a cdc2 kinase (p34) and a p58 subunit, cdc2/p62: a cdc2 kinase and a p62 subunit (cyclin B), the latter is also called M phase-specific histone H1 kinase | Mus musculus |
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