Application | Comment | Organism |
---|---|---|
additional information | zebrafish cdk5 is 96% identical to its human counterpart, Xenopus and most other vertebrate cdk5, the enzyme plays a crucial role in the development of the peripheral nervous system | Danio rerio |
Cloned (Comment) | Organism |
---|---|
- |
Danio rerio |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
siRNA | knockdown of cdk5, results in a reduction in primary sensory neurons of the trigeminal ganglia of the peripheral nervous system, 80% loss of cdk5 protein in 10 hpf embryos | Danio rerio |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Danio rerio | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blastula | 2.5 hpf | Danio rerio | - |
brain | 24hpf embryos | Danio rerio | - |
embryo | at 11.5 h of development, cdk5 transcripts are present in the neural plate at the domains where primary neurons begin to be specified | Danio rerio | - |
eye | especially in the lens capsule of 24hpf embryos | Danio rerio | - |
muscle | 24hpf embryos | Danio rerio | - |
spinal cord | 24hpf embryos | Danio rerio | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + histone H1 | - |
Danio rerio | ADP + phosphorylated histone H1 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Cdk5 | - |
Danio rerio |
cyclin-dependent kinase 5 | - |
Danio rerio |