Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.11.22 extracted from

  • Bayart, E.; Dutertre, S.; Jaulin, C.; Guo, R.B.; Xi, X.G.; Amor-Gueret, M.
    The Bloom syndrome helicase is a substrate of the mitotic Cdc2 kinase (2006), Cell Cycle, 5, 1681-1686.
    View publication on PubMed
Search for more literature for 2.7.11.22

Inhibitors

Inhibitors Comment Organism Structure
roscovitine
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + bloom syndrome helicase Homo sapiens
-
 ADP + phosphorylated bloom syndrome helicase
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HeLa cell
-
 Homo sapiens
-
additional information D1 cell and GM03189B cell Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + bloom syndrome helicase
-
 Homo sapiens ADP + phosphorylated bloom syndrome helicase
-
 ?
ATP + bloom syndrome helicase phosphorylation at Ser-714 and Thr-766, both the N- and C-terminal domains are phosphorylated by Cdc2 Homo sapiens ADP + phosphorylated bloom syndrome helicase
-
 ?
ATP + histone H1
-
 Homo sapiens ADP + phosphorylated histone H1
-
 ?

Synonyms

Synonyms Comment Organism
CDC2 kinase
-
 Homo sapiens