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Literature summary for 2.7.11.22 extracted from

  • Vanstraelen, M.; Torres Acosta, J.A.; De Veylder, L.; Inze, D.; Geelen, D.
    A plant-specific subclass of C-terminal kinesins contains a conserved a-type cyclin-dependent kinase site implicated in folding and dimerization (2004), Plant Physiol., 135, 1417-1429.
    View publication on PubMedView publication on EuropePMC
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Cloned(Commentary)

Cloned (Comment) Organism
expression of CDKA,1 and KCA1/KCA2 in a two-hybrid system in Saccharomyces cerevisiae revealing interactions between the enzyme and the kinesin-like proteins, CDKA,1 binding site mapping by expression of fragments of KCA1/2, overview, co-expression of GFP-tagged CDKA,1 and GFP-tagged KCA1/2 in BY-2 cells and determination of subcellular localization, overview Arabidopsis thaliana

Localization

Localization Comment Organism GeneOntology No. Textmining
nucleus the enzyme contains no nuclear targeting signal sequence and associates tightly with interphase chromatin Arabidopsis thaliana 5634
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Arabidopsis thaliana the enzyme interacts with kinesin-like proteins KCA1 and KCA2 and is required for their activity and protein folding, and is influenced by the phosphorylation status of KCA1 and KCA2, the interaction plays a role in the cell cycle and cell division, overview ?
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 ?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
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 ecotype Columbia
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme interacts with kinesin-like proteins KCA1 and KCA2 and is required for their activity and protein folding, and is influenced by the phosphorylation status of KCA1 and KCA2, the interaction plays a role in the cell cycle and cell division, overview Arabidopsis thaliana ?
-
 ?
additional information the enzyme interacts with kinesin-like proteins KCA1 and KCA2, which possess N-terminal ATP and microtubule binding sites, as well as potential C-terminal CDK phosphorylation sites at positions 698, 849, and 853 in KCA1, and at positions 827 and 831 in KCA2, overview Arabidopsis thaliana ?
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 ?

Synonyms

Synonyms Comment Organism
CDKA,1
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 Arabidopsis thaliana

Cofactor

Cofactor Comment Organism Structure
ATP
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 Arabidopsis thaliana
cyclin B regulatory subunit of CDKA,1 Arabidopsis thaliana